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100% Natrual powder Dictyophora indusiata extract/Dictyophora indusiata extract

2017-04-28



Phallus indusiatus, commonly called the bamboo fungus, bamboo pith, long net stinkhorn, crinoline stinkhorn or veiled lady, is a fungus in the family Phallaceae, or stinkhorns. It has a cosmopolitan distribution in tropical areas, and is found in southern Asia, Africa, the Americas, and Australia, where it grows in woodlands and gardens in rich soil and well-rotted woody material.
Immature fruit bodies of P. indusiatus are initially enclosed in an egg-shaped to roughly spherical subterranean structure encased in a peridium. The "egg" ranges in color from whitish to buff to reddish-brown, measures up to 6 cm (2.4 in) in diameter, and usually has a thick mycelial cord attached at the bottom.As the mushroom matures, the pressure caused by the enlargement of the internal structures cause the peridium to tear and the fruit body rapidly emerges from the "egg". The mature mushroom is up to 25 cm (9.8 in) tall and girded with a net-like structure called the indusium (or less technically a "skirt") that hangs down from the conical to bell-shaped cap. The netlike openings of the indusium may be polygonal or round in shape. Well-developed specimens have an indusium that reaches to the volva and flares out somewhat before collapsing on the stalk. The cap is 1.5–4 cm (0.6–1.6 in) wide and its reticulated (pitted and ridged) surface is covered with a layer of greenish-brown and foul-smelling slime, the gleba, which initially partially obscures the reticulations. The top of the cap has a small hole. The stalk is 7–25 cm (2.8–9.8 in) long, and 1.5–3 cm (0.6–1.2 in) thick. The hollow stalk is white, roughly equal in width throughout its length, sometimes curved, and spongy. The ruptured peridium remains as a loose volva at the base of the stalk. Fruit bodies develop during the night, and require 10–15 hours to fully develop after emerging from the peridium. They are short-lived, typically lasting no more than a few days.At that point the slime has usually been removed by insects, leaving the pale off-white, bare cap surface exposed. Spores of P. indusiatus are thin-walled, smooth, elliptical or slightly curved, hyaline (translucent), and measure 2–3 by 1–1.5 μm.
Medicinal properties have been ascribed to Phallus indusiatus from the time of the Chinese Tang Dynasty when it was described in pharmacopoeia. The fungus was used to treat many inflammatory, stomach, and neural diseases. Southern China's Miao people continue to use it traditionally for a number of afflictions, including injuries and pains, cough, dysentery, enteritis, leukemia, and feebleness, and it has been prescribed clinically as a treatment for laryngitis, leucorrhea, fever, and oliguria (low urine output), diarrhea, hypertension, cough, hyperlipidemia, and in anticancer therapy. Modern science has probed the biochemical basis of these putative medicinal benefits.
The fruit bodies of the fungus contain biologically active polysaccharides. A β-D-glucan called T-5-N and prepared from alkaline extracts has been shown to have anti-inflammatory properties. Its chemical structure is a linear chain backbone made largely of α-1→3 linked D-mannopyranosyl residues, with traces of 1→6 linked D-mannopyrosyl residues.The polysaccharide has tumour-suppressing activity against subcutaneously implanted sarcoma 180 (a transplantable, non-metastasizing connective tissue tumour often used in research) in mice.
Another chemical of interest found in P. indusiatus is hydroxymethylfurfural, which has attracted attention as a tyrosinase inhibitor. Tyrosinase catalyzes the initial steps of melanogenesis in mammals, and is responsible for the undesirable browning reactions in damaged fruits during post-harvest handling and processing, and its inhibitors are of interest to the medical, cosmetics, and food industries. Hydroxymethylfurfural, which occurs naturally in several foods, is not associated with serious health risks. P. indusiatus also contains a unique ribonuclease (an enzyme that cuts RNA into smaller components) possessing several biochemical characteristics that differentiate it from other known mushroom ribonucleases.
Two novel sesquiterpenes, dictyophorine A and B, have been identified from the fruit bodies of the fungus. These compounds, based on the eudesmane skeleton (a common structure found in plant-derived flavours and fragrances), are the first eudesmane derivatives isolated from fungi and were found to promote the synthesis of nerve growth factor in astroglial cells. Related compounds isolated and identified from the fungus include three quinazoline derivatives (a class of compounds rare in nature), dictyoquinazol A, B, and C. These chemicals were shown in laboratory tests to have a protective effect on cultured mouse neurons that had been exposed to neurotoxins.A total synthesis for the dictyoquinazols was reported in 2007.
The fungus has long been recognised to have antibacterial properties: the addition of the fungus to soup broth was known to prevent it from spoiling for several days. Experiments have shown that extracts of P. indusiatus have antioxidant in addition to antimicrobial properties. Mushroom extracts were tested against a variety of bacteria and fungi pathogenic to humans, and in some cases had antimicrobial activity comparable to the antibiotics ampicillin, tetracycline, and nystatin. One of the responsible antibiotics, albaflavenone, was isolated in 2011. It is a sesquiterpenoid that was already known from the soil bacterium Streptomyces albidoflavus. The antioxidant effect of the fungus is due to the presence of polyphenols whose role in reducing cellular damage from oxidative stress is well known.
A 2001 publication in the International Journal of Medicinal Mushrooms attempted to determine its efficacy as an aphrodisiac. In the trial involving only sixteen women, six self-reported the experience of a mild orgasm while smelling the fruit body, and the other ten, who received smaller doses, self-reported an increased heart rate. All of the twenty men tested considered the smell displeasing. The study used fruit bodies found in Hawaii, not the edible variety cultivated in China.